How to Tell If a Snake Has a Respiratory Infection

By Anju Rawat

When it comes to snake health, respiratory infections are among the most common and serious conditions pet owners might encounter. These infections can quickly become life-threatening if not identified and treated promptly. Unlike mammals, snakes don’t cough or sneeze in obvious ways, making respiratory problems particularly challenging to detect for inexperienced keepers. Learning to recognize the subtle signs of respiratory distress in your serpentine companion could mean the difference between swift recovery and tragic loss. This article will guide you through the various indicators of respiratory infections in snakes and provide insights into proper care and treatment options.

Understanding Snake Respiratory Systems

Yellow-bellied Sea Snake (Hydrophis platurus) image via Wikimedia Commons.
Yellow-bellied Sea Snake (Hydrophis platurus) image via Wikimedia Commons.

Snakes possess a unique respiratory anatomy that differs significantly from mammals. They have only one functional lung (the right lung), while the left lung is either vestigial or absent entirely in most species. This specialized respiratory system makes them particularly vulnerable to infections when environmental conditions aren’t optimal. Snakes breathe through a small opening called the glottis, located at the bottom of their mouth, which connects directly to their trachea and lung. Their respiratory system lacks the protective mechanisms found in mammals, such as cilia that sweep away debris, making them more susceptible to pathogens when their immune system is compromised. Understanding this basic anatomy helps explain why respiratory infections develop and how they manifest in these reptiles.

Common Causes of Respiratory Infections

A brown snake with its mouth open on a rock
A brown snake with its mouth open on a rock. Image by David Clode via WordPress Unsplash Instant Images.

Respiratory infections in snakes typically stem from improper husbandry practices rather than contagion from other animals. The most frequent culprit is incorrect temperature within the enclosure, particularly temperatures that are too cool for the species’ needs. Inadequate humidity levels—either too high or too low—can damage the delicate respiratory tissues and create favorable conditions for bacterial growth. Poor ventilation allows bacteria and mold to proliferate in the enclosure, which the snake then inhales. Stress from improper handling, overcrowding, or inappropriate habitat setup can weaken the immune system, making the snake more susceptible to pathogens that would normally be fought off. Additionally, nutritional deficiencies can compromise immune function, leaving the snake vulnerable to opportunistic infections.

Abnormal Breathing Sounds

Colubridae-_Oreocryptophis_porphyraceus_porphyraceus_(Red_Bamboo_Snake)
Kristof Zyskowski & Yulia Bereshpolova, CC BY 2.0 https://creativecommons.org/licenses/by/2.0, via Wikimedia Commons

One of the most recognizable signs of a respiratory infection in snakes is abnormal breathing sounds. A healthy snake breathes silently, with no audible indication of respiration. When infected, snakes often exhibit a distinct wheezing, whistling, or clicking sound during respiration, which indicates fluid or mucus in the airways. Some snakes may make a disturbing “bubbling” noise when breathing, especially when they open their mouths. These sounds are caused by air moving through accumulated mucus in the respiratory tract, similar to congestion in humans. In advanced cases, you might hear a rattling sound when the snake moves, indicating significant fluid buildup in the lungs. These abnormal sounds should always be taken seriously, as they rarely occur in healthy specimens.

Open-Mouth Breathing

The eastern worm snake (Carphophis amoenus amoenus )- image via wikimedia commons
The eastern worm snake (Carphophis amoenus amoenus )- image via wikimedia commons

Healthy snakes typically breathe with their mouths closed, using only their nostrils for air intake. When a snake consistently breathes with its mouth open, particularly when at rest, this strongly indicates respiratory distress. This behavior, sometimes called “gaping,” occurs because the snake is struggling to get sufficient oxygen through its normal respiratory pathways. You might notice the snake extending its neck upward with its mouth open, attempting to maximize airflow to its lungs. Some infected snakes will keep the lower jaw slightly dropped even when not actively breathing. This open-mouth breathing is rarely normal (except in certain species during thermoregulation) and should be considered a significant warning sign requiring immediate attention.

Mucus Discharge

Detailed close-up of a venomous rattlesnake showing its intricate scale patterns and rattle.
Image of a Rattle snake via Pixabay

The presence of mucus around a snake’s mouth, nostrils, or within its oral cavity is a classic sign of respiratory infection. This discharge may range from clear and watery to thick, yellow, or even greenish in color, with the latter indicating a more severe or advanced infection. You might observe bubbles forming at the snake’s nostrils or mouth corners during respiration. In some cases, the mucus may dry around the nostrils, causing visible crusting that can obstruct breathing further. When examining a snake with suspected respiratory issues, gently opening its mouth may reveal strings of mucus between the upper and lower jaws or pooling in the back of the throat. This excessive mucus production represents the body’s attempt to trap and expel pathogens from the respiratory tract.

Labored Breathing and Unusual Postures

Common_Blind_Snake_(Ramphotyphlops_braminus)_鉤盲蛇2
Thomas Brown, CC BY 2.0 https://creativecommons.org/licenses/by/2.0, via Wikimedia Commons

Snakes with respiratory infections often demonstrate visible signs of breathing difficulties beyond open-mouth breathing. You might notice exaggerated chest movements, with the snake’s body visibly rising and falling with each breath in a more pronounced manner than normal. Infected snakes frequently adopt unusual postures to facilitate breathing, such as holding their head and neck elevated off the ground at an awkward angle to straighten their airway. Some may rest with the front portion of their body propped up against enclosure walls or decorations rather than lying flat. A particularly concerning sign is when a snake appears to be working hard to breathe, with each inhalation requiring visible effort. These postures represent the snake’s physical compensation for impaired respiratory function and indicate significant discomfort.

Changes in Activity Level

Porthidium_sp.
Marshal Hedin from San Diego, CC BY 2.0 https://creativecommons.org/licenses/by/2.0, via Wikimedia Commons

A snake suffering from a respiratory infection typically exhibits noticeable changes in its normal behavior patterns, particularly regarding activity levels. Most infected snakes become significantly more lethargic and spend excessive time in hiding spots or completely motionless. They may show little to no interest in exploring their environment even during their usual active periods. When handled, infected snakes often lack their normal muscle tone and may feel “limp” compared to their healthy state. Some snakes may display uncharacteristic irritability or defensiveness when approached, as they feel vulnerable due to their compromised condition. These behavioral changes occur because fighting infection requires considerable energy, leaving the snake with little reserves for normal activities.

Decreased Appetite or Refusal to Eat

Green python on a brown tree
Green python on a brown tree. Image by Tirza van Dijk via WordPress Unsplash Instant Images.

Loss of appetite is commonly observed in snakes with respiratory infections, as the physical stress of illness suppresses their feeding response. A snake that consistently refuses meals when it previously ate reliably should raise immediate health concerns. In some cases, the snake may show initial interest in food but ultimately reject it, possibly due to difficulty swallowing while breathing is compromised. Some infected snakes may attempt to eat but regurgitate shortly afterward because the physical process of consuming prey puts additional strain on their already stressed respiratory system. While healthy snakes might occasionally skip meals for various reasons (shedding, breeding season, etc.), a prolonged feeding strike combined with other respiratory symptoms warrants veterinary attention.

Weight Loss and Dehydration

Close-up of a ball python slithering on gravel, highlighting its unique pattern in warm sunlight.
Close-up of a ball python slithering on gravel, highlighting its unique pattern in warm sunlight.Image by CAMERA TREASURE via Pexels WordPress Instant Images.

Progressive weight loss often accompanies respiratory infections in snakes, becoming evident over weeks as the illness persists. You might notice the snake developing a more triangular body shape as viewed in cross-section, rather than the rounded appearance of a healthy specimen. The spine may become more prominent, and in severe cases, muscle wasting becomes visible along the length of the body. Dehydration frequently accompanies respiratory infections, manifested as wrinkled skin, sunken eyes, or skin that doesn’t bounce back when gently pinched. The mucous membranes in the mouth may appear tacky or dry rather than moist and pink. This combination of weight loss and dehydration reflects the snake’s declining health status and creates a dangerous spiral, as dehydration further compromises the immune system’s ability to fight the infection.

Tilted Head or Neurological Symptoms

gray and black python
gray and black python. Image by Alexander Grey via WordPress Pexel Instant Images.

In advanced or severe respiratory infections, bacteria can spread beyond the respiratory system and affect the brain, leading to neurological symptoms. Affected snakes may hold their head at an abnormal angle or demonstrate difficulty maintaining normal posture. Some may exhibit disorientation, circling behavior, or inability to right themselves when placed on their backs. In particularly concerning cases, you might observe tremors, twitching, or uncoordinated movements when the snake attempts to travel. These neurological symptoms indicate that the infection has become systemic and represent a medical emergency requiring immediate professional intervention. The presence of these signs typically indicates a poor prognosis unless aggressive treatment is initiated promptly.

Confirming a Respiratory Infection

A close up of a green viper curled up
A close up of a green viper curled up. Image by Harshit Suryawanshi via WordPress unsplash Instant Images.

While recognizing the signs is crucial, definitive diagnosis requires veterinary expertise from an experienced reptile specialist. A veterinarian will typically perform a physical examination, listening to the snake’s breathing with a stethoscope and carefully examining the oral cavity and nostrils. They may collect samples of any mucus present for cytology and bacterial culture to identify the specific pathogen involved. In some cases, radiographs (X-rays) may be necessary to visualize the extent of the infection in the lungs and air sacs. Advanced diagnostic techniques might include endoscopy, where a small camera is inserted into the airways to directly visualize the affected tissues. Proper diagnosis is essential because different pathogens (bacteria, fungi, or parasites) require specific treatments, and misidentification can lead to ineffective therapy.

Treatment Approaches

Eastern Garter Snake by D. Gordon E. Robertson image via Wikimedia commons
Eastern Garter Snake by D. Gordon E. Robertson image via Wikimedia commons

Treatment for snake respiratory infections typically involves a multi-faceted approach tailored to the individual case. Antibiotics appropriate for the specific pathogen are usually prescribed, often administered through injections given by the veterinarian or as oral medications you’ll need to give at home. Supportive care is equally crucial, including correcting environmental factors by optimizing temperature and humidity levels in the enclosure. Nebulization therapy, where medication is administered as a fine mist the snake breathes in, might be recommended for direct treatment of the respiratory system. Fluid therapy may be necessary to address dehydration through subcutaneous or intracoelemic injections. In severe cases, oxygen supplementation in a controlled hospital environment might be required. Treatment duration varies but typically continues for weeks, with follow-up appointments to monitor progress.

Prevention Strategies

Kaeng Krachan District
Rushen, CC BY-SA 2.0 https://creativecommons.org/licenses/by-sa/2.0, via Wikimedia Commons

Preventing respiratory infections is far easier and less stressful for both snake and owner than treating established disease. Maintaining proper environmental parameters is paramount—ensure your snake’s enclosure has the correct temperature gradient with an appropriate basking spot temperature for the species. Monitor humidity levels consistently, providing species-appropriate moisture without creating soggy conditions that promote bacterial growth. Proper ventilation in the enclosure prevents stagnant air while maintaining necessary humidity. Regular, thorough cleaning of the habitat removes waste, bacteria, and mold that could trigger respiratory issues. Minimize stress by handling your snake appropriately and providing adequate hiding spots within its enclosure. Quarantine new snakes before introducing them to established collections, and always wash your hands between handling different reptiles to prevent potential pathogen transmission.

When to Seek Emergency Care

Two brown snakes
Two brown snakes. Image by David Clode via Black and white cobra. Image by Boris Smokrovic via WordPress Unsplash Instant Images.

Certain symptoms indicate a severe, life-threatening situation requiring immediate veterinary intervention. If you observe your snake struggling severely to breathe, with exaggerated mouth opening or visible distress, don’t wait to seek help. Neurological symptoms such as star-gazing (looking upward constantly), tremors, or inability to right itself constitute a medical emergency. Significant mucus bubbling from the mouth or nostrils, especially if tinged with blood, indicates advanced infection. Complete refusal to move or respond to stimuli, combined with respiratory symptoms, suggests critical illness. Remember that snakes are masters at hiding illness until conditions become severe, so by the time symptoms are obvious enough for you to notice, the infection is likely already advanced. When in doubt, err on the side of caution—respiratory infections progress rapidly and can become fatal within days if left untreated.

Respiratory infections represent one of the most common yet serious health challenges snake owners face. The subtle nature of early symptoms means vigilance and familiarity with your pet’s normal behavior patterns are essential for timely intervention. By understanding what to look for—from unusual breathing sounds and postures to changes in activity and appetite—you can identify potential problems before they become life-threatening. Remember that respiratory infections rarely resolve without proper treatment, and home remedies are generally ineffective against these potentially fatal conditions. With prompt veterinary care and appropriate environmental corrections, most snakes can recover completely from respiratory infections and return to their healthy, vibrant selves.

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